Health Canada/Environment Canada has issued final screening assessment reports on two gas oils, five heavy fuel oils (HFOs) and three low boiling point naphthas (LBPNs). Relevant toxicological and environmental data are summarised to determine whether these petroleum-derived materials (all industry-restricted) should be classified as “toxic” under Section 64 of the 1999 Canadian Environmental Protection Act (CEPA).
In each case, concern was expressed over their potential carcinogenicity, but calculated margins of exposure (MoEs) for LBPNs and HFOs were considered adequately protective of the general public. Inhalation carcinogenicity studies in laboratory animals were not available on the gas oils, but skin tumours were seen following dermal applications. As this route of exposure is not anticipated for the general public, risk was assessed instead on the basis of non-cancer effects following inhalation, with the resultant MoEs considered adequately health-protective.
For all three groups of chemicals, current levels were not considered to represent a significant adverse risk to the environment.

Environment Canada, Health Canada. Final screening assessments. Petroleum sector stream approach. Gas oils, heavy fuel oils and low boiling point naphthas. July 2013.

http://www.ec.gc.ca/ese-ees/7BF1F2C0-E1EF-4DE7-B3AD-F1F692AC83FF/FSAR_Stream%202%20-%20GOs_EN.pdf

http://www.ec.gc.ca/ese-ees/5A037DB4-5DE9-4258-8E48-137DCA4BE24F/FSAR_Stream%202%20-%20HFOs_EN.pdf

http://www.ec.gc.ca/ese-ees/A9A9EED7-7E57-4081-AF16-7F3EE22D3E5A/FSAR_Stream%202%20-%20LBPNs_EN.pdf

 

The above item was taken from the September 2013 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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