2,5-Dimethylfuran caused eye damage and was probably a severe skin irritant in rabbits. In acute studies, it exhibited a moderate oral and inhalation toxicity in rats and a moderate dermal toxicity in guinea-pigs. A limited investigation involving repeated oral administration to rats evidently found no neurotoxic effects. 2,5-Dimethylfuran induced chromosome effects in mammalian cells in culture, and DNA damage in bacteria. There was no evidence of mutagenicity in (limited) Ames bacterial tests.

Date of Publication: 2002

Number of Pages: 4

CAS Number*: 625-86-5

Format: PDF available for immediate download

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