Alizarin was mutagenic and caused DNA damage in bacterial tests (including that of Ames). In general, it was inactive in a range of genotoxicity screening assays in mammalian cells in culture and did not bind to DNA when administered orally to mice. It was of moderate to low acute oral toxicity in mice and may have suppressed the immune system when administered to mice by repeated intraperitoneal injection. Mild eye irritation occurred in rabbits.

Date of Publication: 1994

Number of Pages: 4

CAS Number*: 72-48-0

Format: PDF available for immediate download

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