Ammonia is irritating to the eyes, skin and respiratory tract of man. At high atmospheric concentrations it causes serious lung injury and death. One study reported a possible skin sensitizing effect in humans, and there are a number of cases of ammonia-induced asthma. In laboratory animals a low acute inhalation toxicity is indicated. The lung was the main target of a single exposure, whilst continuous or repeated exposure over a number of weeks produced damage principally to the lung, respiratory tract, liver, kidney and heart. An increased incidence of lung infections has been noted in inhalation studies in animals. A nasal cancer has developed in a mouse exposed repeatedly to “ammonia vapour”. No convincing evidence of mutagenicity was found in bacterial assays, including an Ames test.

Date of Publication: 1995

Number of Pages: 9

CAS Number*: 7664-41-7

Format: PDF available for immediate download

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