The acute oral and dermal toxicity of chamomile oils was low in rats and rabbits respectively. Oral administration of chamomile tea to humans may cause mild effects on the circulatory system and induce sleep, with excessive consumption possibly leading to gastric problems. Effects on rodent behaviour have been seen after oral administration of chamomile oils and injection of extracts. Repeated injections of chamomile oil caused liver enlargement in rats. In a study on bacteria exposed to Roman chamomile oil, there was no evidence of mutagenicity (in an Ames assay) or of DNA damage.
Date of Publication: 1992
Number of Pages: 7
CAS Number*: 8015-92-7
8002-66-2
Format: PDF available for immediate download
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