Cocamidopropyl betaine (CAPB) is a skin irritant in man and an eye irritant in rabbits. The reports of skin sensitization in man are mainly a consequence of the unreacted starting materials present in most samples of CAPB. A moderate to low acute oral toxicity was demonstrated in rodents. Repeated oral studies in rats identified the stomach as the main target of toxicity. Limited dermal studies in mice found no evidence of carcinogenicity. Mutagenic potential was not detected in mammalian cells in culture or in limited Ames bacterial tests.

Date of Publication: 1999

Number of Pages: 7

CAS Number*: 61789-40-0

86438-79-1

Format: PDF available for immediate download

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