Copper naphthenate was generally of low acute oral and dermal toxicity in rodents and rabbits respectively. Single oral doses produced gastro-intestinal lesions in rats and liver abnormalities in a lamb. Repeated intraperitoneal injection into pregnant rats did not affect the offspring. Copper naphthenate was inactive in tests for chromosomal damage or mutations in mammalian cells in culture and in an Ames bacterial test. No (dominant lethal) mutations were seen when female mice were mated with orally-exposed males.
Date of Publication: 1999
Number of Pages: 9
CAS Number*: 1338-02-9
Format: PDF available for immediate download
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