Methyl n-amyl ketone (MAK) has been reported to be a skin, eye, nose and throat irritant in man and laboratory animals. It did not exhibit any skin sensitizing potential in human or guinea-pig studies. Acute toxicity in laboratory animals was low by the dermal route, but moderate following oral administration. Inhalation of the vapour by rats, mice and guinea-pigs caused central nervous system effects. Mild effects on the liver and kidney were described following oral studies in rats. MAK enhanced the toxicity of another solvent.

Date of Publication: 1988

Number of Pages: 7

CAS Number*: 110-43-0

Format: PDF available for immediate download

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