Tripropylene glycol diacrylate (TPGDA) was an irritant to the skin of rabbits. It has demonstrated a moderate to strong sensitizing potential in guinea pigs and one case of sensitization has been reported in man. Cross-reactions with other acrylates may occur. It was of low acute oral and dermal toxicity in rats and rabbits respectively. Central nervous system effects were apparent in rabbits following repeated dermal applications. Some evidence of mutagenic activity was seen in mammalian cells in culture but an Ames bacterial test apparently showed no evidence of mutagenicity.

Date of Publication: 1991

Number of Pages: 5

CAS Number*: 42978-66-5

Format: PDF available for immediate download

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