A draft monograph assessing the carcinogenic potential of cobalt and a number of organic and inorganic cobalt compounds has been issued by the NTP. The report aims to determine whether these substances should be included in the RoC, which lists chemicals known, or reasonably anticipated, to be human carcinogens, and to which a significant number of people residing in the US are exposed. In this case, the NTP recommended listing cobalt and compounds that can release cobalt ions in vivo as “reasonably anticipated to be a human carcinogen”. This conclusion was reached based on sufficient evidence of carcinogenicity at multiple sites in exposed rodents.

US National Toxicology Program (2015). Peer-review draft. Report on Carcinogens monograph on cobalt and certain cobalt compounds. 5 June 2015. http://ntp.niehs.nih.gov/ntp/about_ntp/monopeerrvw/2015/july/cobalt_draftmonograph.pdf

 

 

The above items were taken from the July 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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