ECVAM has published its final recommendation on the human cell line activation test (h-CLAT), a new in vitro toxicological method designed to predict the potential of a chemical to cause skin sensitisation. ECVAM considers that the data generated should prove valuable as part of an integrated approach to testing and assessment, together with complementary information, but does not recommend its use as a standalone test.

European Union Reference Laboratory for Alternatives to Animal Testing. EURL ECVAM recommendation on the human Cell Line Activation Test (h-CLAT) for skin sensitisation testing. February 2015. https://eurl-ecvam.jrc.ec.europa.eu/news/news_docs/eurl-ecvam-recommendation-on-the-human-cell-line-activation-test-h-clat-for-skin-sensitisation-testing

 

The above items were taken from the April 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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