Based on their very low toxicities, EFSA has concluded that numerical acceptable daily intake (ADI) values are not needed for acacia gum, glycerol, soybean hemicellulose or lecithins. For most of these substances, EFSA also considers estimated dietary intakes for the general population to be of no safety concern; for soybean hemicellulose a safety risk is “very unlikely” as dietary exposures are probably negligible. EFSA also recommends that levels of potentially allergenic residual proteins in this food additive should be reduced as much as possible.

Regarding polyglycerol polyricinoleate, the ADI of 7.5 mg/kg bw set by the Scientific Committee for Food in 1978 was increased to 25 mg/kg bw/day, based on a 2-year study in which no adverse effects were observed in rats fed 2500 mg/kg bw/day.

European Food Safety Authority (2017). Panel on Food Additives and Nutrient Sources added to Food (ANS). Re-evaluations of:

Acacia gum (E 414) as a food additive.

Glycerol (E 422) as a food additive.

Lecithins (E 322) as a food additive.

Polyglycerol polyricinoleate (E 476) as a food additive.

Soybean hemicellulose (E 426) as a food additive.


The above items were taken from the May 2017 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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