None of 10 novel and 17 emerging BFRs assessed by EFSA had sufficient occurrence, exposure or toxicity data to enable risk characterisation. Instead, EFSA identified those substances which should be prioritised for future assessment.

From available toxicity data, convincing evidence of genotoxic carcinogenicity led EFSA to conclude that further surveillance of the occurrence of the following substances in food and the environment was warranted:

  • tris(2,3-dibromopropyl)phosphate (TDBPP)
  • dibromoneopentyl glycol (DBNPG)

Limited data on environmental behaviour suggested these two chemicals could cause concern for bioaccumulation:

  • 1,2-bis(2,4,6-tribromophenoxy)ethane (BTBPE)
  • hexabromobenzene (HBB)

Modelling for persistence and bioaccumulation supported the above conclusion, and suggested that the following eight chemicals may also be of concern, and should be subject to further in-depth studies:

  • 5,6-dibromo-1,10,11,12,13,13-hexachloro-11-tricyclo[,9]tridecene (DBHCTD)
  • N,N’-ethylenebis(tetrabromophthalimide) (EBTEBPI)
  • hexabromocyclodecane (HBCYD)
  • 1,2,3,4,7,7-hexachloro-5-(2,3,4,5-tetrabromophenyl)-bicyclo[2.2.1]hept-2-ene (HCTBPH)
  • pentabromotoluene (PBT)
  • pentabromobenzyl acrylate (PBB-Acr)
  • pentabromoethylbenzene (PBEB)
  • 1,2,4,5-tetrabromo-3,6-dimethylbenzene (TBX)

European Food Safety Authority. Panel on Contaminants in the Food Chain (CONTAM). Scientific opinion on emerging and novel brominated flame retardants (BFRs) in food. EFSA Journal 2012, 10(10): 2908.


The above item was taken from the November 2012 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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