EFSA has published a draft opinion on the health risks posed by CPs in food and feed. BMDL10 values of 2.3 mg/kg bw/day (for nephritis in male rats) and 36 mg/kg bw/day (for increased relative kidney weights in male and female rats) were selected as the points of departure (PoDs) for short-chain (SCCPs) and medium-chain (MCCPs) mixtures, respectively. Human dietary exposures were considered not to be of concern for these chemical groups (albeit the exposure estimates were limited, chronic intake being based only on the consumption of “fish meat”). Toxicological and exposure data were too limited for a human health risk assessment of long-chain CP mixtures (LCCPs).

European Food Safety Authority (2019). Panel on Contaminants in the Food Chain (CONTAM). Scientific opinion on the risk for animal and human health related to the presence of chlorinated paraffins in feed and food. http://www.efsa.europa.eu/en/consultations/call/public-consultation-draft-efsa-opinion-0

 

The above items were taken from the September 2019 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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