In December 2019, EFSA finalised its opinion on dibutyl phthalate (DBP), butylbenzyl phthalate (BBP), bis(2-ethylhexyl) phthalate (DEHP), diisononyl phthalate (DINP) and diisodecyl phthalate (DIDP), which are currently authorised for use in plastic FCMs within Europe. A group tolerable daily intake (TDI) of 0.05 mg/kg bw (as DEHP equivalents) was established for DBP, BBP, DEHP and DINP on the basis of male reproductive toxicity. Although DIDP is recognised also to have toxic effects on reproduction, its mode of action is dissimilar to the anti-androgenic effect displayed by the other phthalates under consideration. Therefore, it was not added to the new group TDI, and instead retained its individual TDI of 0.15 mg/kg bw for liver effects.

European Food Safety Authority (2019). Panel on Food Contact Materials, Enzymes and Processing Aids (CEP). Update of the risk assessment of di-butylphthalate (DBP), butyl-benzyl-phthalate (BBP), bis(2-ethylhexyl)phthalate (DEHP), di-isononylphthalate (DINP) and di-isodecylphthalate (DIDP) for use in food contact materials.


The above items were taken from the January/February 2020 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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