A recent draft report from EFSA reviews the human health effects of caffeine, and considers its possible interactions with alcohol, other components of energy drinks (taurine and D-glucurono-γ-lactone) and synephrine (which is present in combination with caffeine in some food supplements). Single doses of up to 200 mg caffeine are considered unlikely to induce clinically relevant changes in blood pressure, myocardial blood flow, hydration status or body temperature. Daily intakes of up to 400 mg also do not raise safety concerns for adults in the general population, although for pregnant women a lower limit of 200 mg/day is proposed to protect the foetus.

European Food Safety Authority (2015). Draft scientific opinion on the safety of caffeine. http://www.efsa.europa.eu/en/consultations/call/150115.pdf

The above items were taken from the January/February 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)


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