Asked to comment on the recent epidemiology study that associated high urinary bisphenol A concentrations with an increased risk of cardiovascular disease and diabetes (see Toxicology and Regulatory News 2008, 47(10), 180), two Panels of the European Food Safety Authority concluded that the study did not provide sufficient evidence to establish a causal link. They felt that a single urine sample could not be used as an indicator of exposure during the time required for the development of these diseases, and thus there was no need to revise the Tolerable Daily Intake of 0.05 mg/kg bw/day previously derived by the (former) AFC Panel.

[Statement of EFSA prepared by the Unit on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF) and the Unit on Assessment Methodology (AMU) on a study associating bisphenol A with medical disorders. Issued on 22 October 2008. The EFSA Journal 2008, 838, 1. Available at on the EFSA website.] {179539}

The above item is taken from the December 2008 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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