The US Agency for Toxic Substances and Disease Registry has made available online nine final toxicological profiles. These profiles provide a thorough review of the toxicological and epidemiological data for each substance, and an evaluation of the risk to human health from a number of different routes of exposure. Also developed in this process are Minimal Risk Levels (MRLs), defined as an estimate of daily human exposure to a substance that is likely to be without an appreciable risk of adverse non-cancer health effects over a specified duration of exposure.

  • 1,3-butadiene
  • cadmium
  • carbon monoxide
  • chromium
  • 1,4-dioxane
  • manganese
  • phosphate ester
  • flame retardants
  • radon
  • vanadium

In addition, the ATSDR website has been updated with several addenda to existing toxicological profiles. These are not peer-reviewed – unlike the main profiles – but provide information from the scientific literature which is intended to be read in conjunction with the full profile. Recent addenda have been published for:

  • 2,3-benzofuran
  • carbon disulfide
  • chlorinated dibenzo-para-dioxins
  • hydrogen sulfide
  • pentachlorophenol

US Agency for Toxic Substances and Disease Registry Toxicological Profiles.

All profiles and addenda are accessible through the alphabetical list.

http://www.atsdr.cdc.gov/toxprofiles/index.asp

The above item was taken from the January–February 2013 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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