Newly published IARC monographs fully cover the agency’s June 2013 meeting discussing the carcinogenic risks of a range of drugs and herbal products (volume 108). The overall evaluations are summarised as follows:

“Probably carcinogenic to humans” (Group 2A):

  • pioglitazone

“Possibly carcinogenic to humans” (Group 2B):

  • Aloe vera
  • digoxin
  • Ginkgo biloba
  • goldenseal
  • hydrochlorothiazide
  • kava
  • pentosan polysulfate sodium
  • primidone
  • pulegone
  • sulfasalazine
  • triamterene



“Not classifiable as to its carcinogenicity to humans” (Group 3):

  • methylene blue
  • rosiglitazone

International Agency for Research on Cancer (2015). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Volume 108. Some drugs and herbal products.


The above item was taken from the November 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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