Health Canada has evaluated the toxicological data on perfluorooctanoic acid (PFOA) and has set a maximum acceptable concentration (MAC) of 0.2 μg/L in the drinking water. The MAC was derived using pharmacokinetic modelling on the most sensitive endpoint, liver cell hypertrophy in orally-exposed rats, and is considered to be “sufficiently protective” of both cancer and non-cancer effects.
Health Canada (2016). Perfluorooctanoic acid (PFOA) in drinking water. June 2016. http://www.healthycanadians.gc.ca/health-system-systeme-sante/consultations/acide-perfluorooctanoic-acid/alt/perfluorooctanoic-eng.pdf
The above items were taken from the December 2016 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)News Home Guest Write For Us? Contact Us