Health Canada has evaluated the toxicological data on perfluorooctanoic acid (PFOA) and has set a maximum acceptable concentration (MAC) of 0.2 μg/L in the drinking water. The MAC was derived using pharmacokinetic modelling on the most sensitive endpoint, liver cell hypertrophy in orally-exposed rats, and is considered to be “sufficiently protective” of both cancer and non-cancer effects.

Health Canada (2016). Perfluorooctanoic acid (PFOA) in drinking water. June 2016. http://www.healthycanadians.gc.ca/health-system-systeme-sante/consultations/acide-perfluorooctanoic-acid/alt/perfluorooctanoic-eng.pdf

 

The above items were taken from the December 2016 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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