Health Canada has reviewed the toxicological data on various chromium species and has set a maximum acceptable concentration (MAC) of 100 μg/L for total chromium in drinking water. The proposed MAC is based on the health effects of chromium(VI), and considers cancer and non-cancer effects together. Pharmacokinetic and benchmark dose modelling were conducted on the most sensitive endpoint, diffuse hyperplasia of the small intestine, to derive the MAC.

Health Canada (2015). Chromium in drinking water. July 2015. http://www.healthycanadians.gc.ca/health-system-systeme-sante/consultations/chromium-chrome/alt/chromium-chrome-eng.pdf

 

The above items were taken from the December 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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