An October 2018 meeting of the International Agency for Research on Cancer (IARC) discussed the carcinogenicity of the following chemicals:

  • 2-amino-4-chlorophenol
  • 2-chloronitrobenzene
  • 4-chloronitrobenzene
  • 1,4-dichloro-2-nitrobenzene
  • 2,4-dichloro-1-nitrobenzene
  • para-nitroanisole
  • N,N-dimethylacetamide
  • ortho-phenylenediamine and its dihydrochloride salt

All nine chemicals were classified as “possibly carcinogenic to humans” (Group 2B) based on sufficient evidence of carcinogenicity in laboratory animals and a lack of data or inadequate evidence in humans.

Van den Berg M et al. (2018). Carcinogenicity of some nitrobenzenes and other industrial chemicals. Lancet Oncology. November 2018. https://www.thelancet.com/pdfs/journals/lanonc/PIIS1470-2045(18)30823-4.pdf

 

The above items were taken from the December 2018 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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