Newly published IARC monographs cover the agency’s June 2012 meeting on engine exhausts and some nitroarenes (Volume 105) and the October 2012 meeting on several chlorinated solvents and some of their metabolites (Volume 106). The overall evaluations are summarised as follows:

Volume 105:

“Carcinogenic to humans” (Group 1):

  • diesel engine exhaust

“Probably carcinogenic to humans” (Group 2A):

  • 6-nitrochrysene
  • 1-nitropyrene

“Possibly carcinogenic to humans” (Group 2B):

  • gasoline engine exhaust
  • 3,7-dinitrofluoranthene
  • 3,9-dinitrofluoranthene
  • 1,3-dinitropyrene
  • 1,6-dinitropyrene
  • 1,8-dinitropyrene
  • 3-nitrobenzanthrone
  • 2-nitrofluorene
  • 4-nitropyrene

Volume 106:

“Carcinogenic to humans” (Group 1):

  • trichloroethylene

“Probably carcinogenic to humans” (Group 2A):

  • tetrachloroethylene
  • chloral hydrate

“Possibly carcinogenic to humans” (Group 2B):

  • dichloroacetic acid
  • trichloroacetic acid
  • 1,1,1,2-tetrachloroethane
  • 1,1,2,2-tetrachloroethane

International Agency for Research on Cancer (2013). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.

Volume 105. Diesel and gasoline engine exhausts and some nitroarenes.

Volume 106. Trichloroethylene, tetrachloroethylene and some other chlorinated agents.


The above items were taken from the January/February 2014 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here

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