- an acceptable daily intake (ADI) of 5 mg/kg bw was assigned to advantame, based on maternal toxicity in a developmental toxicity study in rabbits
- due to its low toxicity and low estimates of dietary exposure, an ADI “not specified” was established for glucoamylase from, and expressed in, Trichoderma reesei
- the temporary group ADI of 12.5 mg/kg bw for glycerol ester of gum rosin and glycerol ester of wood rosin (GEWR) was withdrawn, and an ADI of 25 mg/kg bw was re-established for GEWR
- for nisin, the previous ADI of 33,000 units/kg bw [40 units = 1 µg] was withdrawn and an ADI of 2 mg/kg bw was established based on the results of a 13-week toxicity study in rats
- the temporary ADI “not specified” was retained for octenyl succinic acid modified gum arabic, pending submission (by the end of 2013) of additional data on its stability in food
JECFA (2014). Safety evaluation of certain food additives. Prepared by the seventy-seventh meeting of the Joint FAO/WHO Expert Committee on Food Additives. WHO Food Additives Series 68.
The above items were taken from the January/February 2014 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)News Home Guest Write For Us? Contact Us