The technical report from JECFA’s 84th meeting (held in June 2017) has been released. The following decisions on certain food additives are of particular interest:

  • Brilliant Blue FCF: a newly available long-term rat study prompted the revision of the acceptable daily intake (ADI) from 0-12.5 to 0-6 mg/kg bw
  • β-Carotene-rich extract from Dunaliella salina: no health concern when used as a food colourant
  • Fast Green FCF: newly available data gave no reason to revise the existing ADI of 0-25 mg/kg bw
  • Gum ghatti: as there was considered to be no systemic exposure to this material after ingestion (due to its polysaccharide structure), and it showed a lack of general systemic toxicity and genotoxic activity, an ADI “not specified” was established
  • Jagua (Genipin-Glycine) Blue: the Committee was unable to complete its evaluation because of a limited biochemical and toxicological database, as well as a low margin of exposure with the NOAEL derived from 90‑day toxicity studies
  • Metatartaric acid: as hydrolysis to tartaric acid occurs after ingestion (prior to absorption), metatartaric acid was included in the group ADI of 0-30 mg/kg bw for tartaric acid and its simple salts
  • Tamarind seed polysaccharide: an ADI “not specified” was established, due to a lack of concern regarding general toxicity, genotoxicity and reproductive and developmental toxicity
  • Tannins: it was not possible to evaluate tannins as used in wine-making, due to the absence of identification information
  • Yeast extracts containing mannoproteins: JECFA considered it “unlikely that there would be a health concern” for their use as wine stabilisers.

Joint FAO/WHO Expert Committee on Food Additives (2017). Evaluation of certain food additives. Eighty-fourth report. WHO Technical Report Series 1007.


The above items were taken from the January-February 2018 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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