The WHO food additives monograph has been released from JECFA’s 79th meeting, held in June 2014. The main conclusions of the report are as follows:

  • Carrageenan in infant formulae: use at concentrations of up to 1000 mg/L is of no toxicological concern.
  • Citric and fatty acid esters of glycerol (“CITREM”) in infant formulae: no concern at concentrations of up to 9 g/L.
  • Lutein esters from Mexican marigold (Tagetes erecta): a temporary acceptable daily intake (t-ADI) of “not specified” was established.
  • Octenyl succinic acid (OSA)-modified gum arabic: the t-ADI “not specified” will be withdrawn unless adequate data to complete the safety evaluation are submitted by the end of 2015.
  • Paprika extract used as a food colour: an ADI of 1.5 mg/kg bw (expressed as total carotenoids) was established.
  • Pectin in infant formulae: concern was expressed that growth might be impaired at the maximum proposed use level of 0.5%.

A number of flavouring agents in the following groups were also evaluated. Most were considered to be of “no safety concern” based on current estimates of dietary exposure:

  • aliphatic and alicyclic hydrocarbons
  • aliphatic and aromatic ethers
  • ionones and structurally-related substances (additional data required to complete evaluation)
  • miscellaneous nitrogen-containing substances
  • monocyclic and bicyclic secondary alcohols, ketones and related esters
  • phenol and phenol derivatives
  • phenyl-substituted aliphatic alcohols and related aldehydes and esters
  • sulphur-containing heterocyclic compounds

Joint FAO/WHO Expert Committee on Food Additives (2015). Safety evaluation of certain food additives. Seventy-ninth meeting, Geneva, 17‑26 June 2014. WHO Food Additives Series 70. World Health Organisation. http://apps.who.int/iris/bitstream/10665/171781/3/9789240693982_eng.pdf?ua=1

 

 

The above items were taken from the July 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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