The WHO food additives monograph has been released from JECFA’s 79th meeting, held in June 2014. The main conclusions of the report are as follows:
- Carrageenan in infant formulae: use at concentrations of up to 1000 mg/L is of no toxicological concern.
- Citric and fatty acid esters of glycerol (“CITREM”) in infant formulae: no concern at concentrations of up to 9 g/L.
- Lutein esters from Mexican marigold (Tagetes erecta): a temporary acceptable daily intake (t-ADI) of “not specified” was established.
- Octenyl succinic acid (OSA)-modified gum arabic: the t-ADI “not specified” will be withdrawn unless adequate data to complete the safety evaluation are submitted by the end of 2015.
- Paprika extract used as a food colour: an ADI of 1.5 mg/kg bw (expressed as total carotenoids) was established.
- Pectin in infant formulae: concern was expressed that growth might be impaired at the maximum proposed use level of 0.5%.
A number of flavouring agents in the following groups were also evaluated. Most were considered to be of “no safety concern” based on current estimates of dietary exposure:
- aliphatic and alicyclic hydrocarbons
- aliphatic and aromatic ethers
- ionones and structurally-related substances (additional data required to complete evaluation)
- miscellaneous nitrogen-containing substances
- monocyclic and bicyclic secondary alcohols, ketones and related esters
- phenol and phenol derivatives
- phenyl-substituted aliphatic alcohols and related aldehydes and esters
- sulphur-containing heterocyclic compounds
Joint FAO/WHO Expert Committee on Food Additives (2015). Safety evaluation of certain food additives. Seventy-ninth meeting, Geneva, 17‑26 June 2014. WHO Food Additives Series 70. World Health Organisation. http://apps.who.int/iris/bitstream/10665/171781/3/9789240693982_eng.pdf?ua=1
The above items were taken from the July 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)News Home Guest Write For Us? Contact Us