Based on the US Environmental Protection Agency’s estimate of the human cancer potency of PCBs of 2.0 (mg/kg-day)‑1, the OEHHA has calculated a no significant risk level (NSRL, defined as the daily level posing a 10‑5 lifetime risk of cancer) for PCBs in food of 0.35 µg/day for a 70‑kg person. A maximum allowable dose level (MADL) of 2.3 µg/day for a 58-kg woman was adopted for PCBs (in food), based on developmental toxicity in a primate study.

Office of Environmental Health Hazard Assessment (OEHHA) of the California Environmental Protection Agency (Cal/EPA).
Proposition 65 Implementation Program. Specific regulatory levels posing no significant risk: polychlorinated biphenyls.
13 April 2012

The above item was taken from the May 2012 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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