Several new listings are included in the latest RoC, which now contains a total of 248 substance profiles on agents that may potentially pose a human cancer hazard. Each monograph reviews the evidence for carcinogenicity (from human and animal studies), and supporting data on the possible carcinogenic mechanisms involved.

Among the new listings, trichloroethylene is upgraded to be classified as “known to be a human carcinogen” on the basis of human, animal and mechanistic studies linking exposure to kidney cancer. Cobalt, and several compounds that release cobalt ions in vivo, are “reasonably anticipated to be human carcinogens”.

US National Toxicology Program (2016). Report on carcinogens, fourteenth edition. November 2016

http://ntp.niehs.nih.gov/update/2016/11/rocrelease/index.html

 

The above items were taken from the December 2016 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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