The Scientific Steering Committee of the VKM has drawn up a report describing “the most relevant theoretical principles” for various types of combined toxic effects from multiple chemical exposures. The different schemes that have been developed (e.g. by the UK Committee on Toxicity and the Danish Veterinary and Food Administration) are outlined. In most cases they are considered “not suitable for practical use in the Scientific Panels of the VKM”. A flow chart has been developed and will be tested as a tool for assessing combined effects of multiple exposures.

[Opinion of the Scientific Steering Committee of the Norwegian Scientific Committee for Food Safety. Combined toxic effects of multiple chemical exposures. Report 1: 2008. Adopted 7 April 2008 (available at http://www.vkm.no/eway/library/openForm.aspx?param1=17786¶m5=read).] {178818}

The above item was taken from the October 2008 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).