Consumer health assessments of dental products

Client

A major multinational provider of oral healthcare products.

Background

Bibra scientists were asked to assess the health risks to consumers associated with exposures to various ingredients in five oral healthcare products, designed to be applied directly to the teeth.

Project goals

Assess the potential health risks posed to consumers using the product by reviewing the available toxicological data on relevant chemical ingredients.

Approach

The available literature was searched to identify data relevant to the toxic potential of each product ingredient. Where available, Expert Group evaluations and derived Health Criteria Values (HCVs) were the main focus. Adverse local effects to the teeth and oral soft tissues were considered. Systemic absorption was considered possible if the product was swallowed or absorbed through the gums. Relevant worst-case exposures (involving both acute and repeated dose scenarios) were considered, allowing bibra to conclude on the likely consumer health risks.

Project outcome

Bibra provided the client with critical hazard and risk assessments of the five products.

Project leader

Beth O’Connell

Pete Watts

 

Cosmetics

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