UK Environment Agency (EA)

Contaminated land

Development of toxicity collations using the principles outlined in SR2 (formerly CLR9) as part of the Contaminated Land Exposure Assessment (CLEA). As a consequence, bibra has evaluated the mammalian toxicology of a large number of substances culminating in reports that recommend oral and inhalation health criteria values (HCVs). Reports on the following chemicals have been published: benzene; toluene; ethylbenzene; xylenes; mercury; selenium; arsenic; nickel; cadmium; phenol; dioxins, furans and dioxin-like PCBs. These can be found on the EA’s website via the National Archives ( Draft reports have also been prepared on: chromium; cyanide (inorganic); lead (inorganic); lead (organic); polycyclic aromatic hydrocarbons.


Contaminated air

Based on an assessment and distillation of the conclusions of authoritative reviews produced by national and international organisations, together with an evaluation of the impact of more recent primary literature, draft reports have been prepared on acrylonitrile, antimony, carbon tetrachloride, chloromethane, dimethyl formamide, hydrogen cyanide, phenol, selenium, tetrachloroethane, trichloroethylene and vinyl chloride. The objective is the derivation of tolerable concentrations in air (TCA). The finalized reports will ultimately feed into the derivation and adoption of an environmental assessment level (EAL) for use within the Environmental Permitting Regulations.


Benchmark dose (BMD) analysis

Identification of key cancer data on selected soil contaminants in preparation for benchmark dose analyses. Estimation of BMDL10 values of a laboratory animal carcinogen were determined using the US EPA BMD software.


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