ECHA’s Committee for Risk Assessment (RAC) has recently evaluated the dose-response relationship for the carcinogenicity of CTPHT, establishing lifetime excess cancer risk estimates for workers and the general population exposed via the oral, dermal and/or inhalation routes. The report also discusses the mechanism of (carcinogenic) action of polycyclic aromatic hydrocarbons (PAHs), the major constituents of CTPHT.

European Chemicals Agency (2018). Note on reference dose-response relationship for the carcinogenicity of pitch, coal tar, high temperature and on PBT and vPvB properties. 8 June 2018. Available at https://echa.europa.eu/applying-for-authorisation/evaluating-applications

 

The above items were taken from the August 2018 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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