Member State competent authorities and the European Chemicals Agency may prepare Annex XV dossiers for the identification of SVHCs which are carcinogenic, mutagenic or reprotoxic (CMR), persistent, bioaccumulative and toxic (PBT), very persistent and very bioaccumulative (vPvB), or of an equivalent level of concern (ELoC). The latest dossiers have been released by the Austrian (in co‑operation with Slovakian), Norwegian and Swedish authorities, and cover:

  • 2-benzyl-2-dimethylamino-4′-morpholinobutyrophenone as CMR (reprotoxic)
  • 2-methyl-1-(4-methylthiophenyl)-2-morpholinopropan-1-one as CMR (reprotoxic)
  • diisohexyl phthalate as CMR (reprotoxic)
  • perfluorobutane sulfonic acid (PFBS) and its salts as ELoC (human health and environmental effects)

European Chemicals Agency (2019). Annex XV reports. Proposals for identification of substances of very high concern on the basis of the criteria set out in REACH Article 57. August 2019. Reports available via


The above items were taken from the October 2019 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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