Finalised opinions adopted by the Scientific Committee on Consumer Safety for cosmetic ingredients, assess hydroxyethoxyphenyl butanone (HEPB) and polyhexamethylene biguanide hydrochloride (PHMB). The use of HEPB as a cosmetic preservative in rinse-off, oral care and leave-on products was not considered safe at the proposed concentration of 2%, but a lower concentration of 0.7% was supported. The use of PHMB as a preservative in all cosmetic products at up to 0.1% was considered safe (in light of new dermal absorption studies).

Scientific Committee on Consumer Safety (2017). Opinions on:

Ethylzingerone – ‘hydroxyethoxyphenyl butanone’ (HEPB). SCCS/1582/16. Final version.

Polyaminopropyl biguanide (PHMB). Submission III. SCCS/1581/16. Final version.


The above items were taken from the May 2017 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

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