The EC Scientific Committee on Consumer Safety has recently adopted opinions on the use in cosmetic products of:

  • deoxyarbutin
  • 2,6-dihydroxyethylaminotoluene
  • HC Yellow No. 17
  • phenylene bis-diphenyltriazine
  • 2,5,6-triamino-4-pyrimidinol sulphate

Although the risk of occasional sensitisation reactions could not be excluded, 2,5,6-triamino-4-pyrimidinol sulphate (at up to 0.5% ‘on-head’) and HC Yellow No. 17 (at up to 0.5%) were otherwise considered safe in hair dyes. The safety of 2,6-dihydroxyethylaminotoluene was also supported at concentrations of up to 1% ‘on-head’, when used in the absence of nitrosating agents. Concerns were, however, raised over the formation of hydroquinone by deoxyarbutin in face creams (at up to 3%), and the use of phenylene bis-diphenyltriazine (for which a genotoxic potential could not be excluded) as a UV filter in sunscreens (at up to 10%).

European Commission (2015). Opinions (dated June-July 2015) on:

Deoxyarbutin (tetrahydropyranyloxy phenol). SCCS/1554/15.

2,6-Dihydroxyethylaminotoluene (Colipa No. A138). SCCS/1563/15.

HC Yellow No. 17 (B121). SCCS/1559/15.

2,5,6-Triamino-4-pyrimidinol sulfate (Colipa No. A143). SCCS/1561/15.

UV filter S86 (phenylene bis-diphenyltriazine). SCCS/1556/15.


The above items were taken from the October 2015 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here)

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