TCEQ has released a revised draft DSD on ethylene oxide, a substance that is utilised in many industrial applications and is particularly useful as a sterilant for medical devices. TCEQ carried out a carcinogenic dose-response assessment and derived a unit risk factor of 2.5 x 10-6 per ppb (1.4 x 10-6 per μg/m3), using lymphoid cancer as the critical endpoint. The inhalation Effect Screening Level (ESL), the concentration in the air that is considered safe for the general population (including vulnerable sub-populations), was determined to be 4 ppb (7.1 μg/m3).

Texas Commission on Environmental Quality (2020). Development Support Document. Ethylene oxide. Revised Draft, January 31, 2020. https://www.tceq.texas.gov/assets/public/implementation/tox/dsd/proposed/eto.pdf

 

The above items were taken from the April 2020 issue of Toxicology and Regulatory News which is sent automatically to members of bibra.

News Home Guest Write For Us? Contact Us