Volume 46, Number 4

April 2007 

PART I: WORLD NEWS


INTERNATIONAL

WHO drinking water guidelines on cyanide, cyanogen chloride and dichloroisocyanurate
JMPR pesticide monographs
JECFA veterinary residues
JECFA evaluations of food additives and contaminants – 67th meeting
Three new environmental health criteria (EHC) documents
IPCS – less doubt on uncertainty in exposure assessments

EUROPEAN UNION

EU risk assessment report on 2-methoxy-2-methylbutane and a draft on methenamine
SCCP deliberations on…
… hydroxypropyl bis(N-hydroxyethyl-para-phenylenediamine) hydrochloride
… N-phenyl-para-phenylenediamine
… 3-nitro-para-hydroxyethylaminophenol and HC Blue No. 2
… meta-aminophenol, phenyl methyl pyrazolone and 2,6-dihydroxy-3,4-dimethylpyridin
EC draft guidance document for setting AOELs for plant protection products
EFSA assesses adequacy of national MRLs
Proposed revisions to pesticide toxicity data requirements reviewed by EFSA
EFSA assesses cyanogenic compounds in animal feed
More food-contact assessments by EFSA
Maximum levels of aflatoxins in nuts – EFSA gives opinion
EFSA press statement on MON 863 – a genetically modified maize

UNITED KINGDOM

COC discuss DNELs in the context of REACH
COM Statement on the mutagenicity of acrylamide
Ethaboxam – a COM Statement recommends more genotoxicity tests
Prostate cancer and pesticide exposure considered by the COC
COT to discuss food additives and behaviour in children, and also the effects of dioxin on rat development
SACN reviews vitamin D
Assessing the risk of short-term exposure to genotoxic carcinogens – further COC debate

UNITED STATES

EPA IRIS draft toxicological review for 1,1,1-trichloroethane
NTP studies on sodium dichromate dihydrate (SDD)
Submissions to the EPA HPV Program
EPA nanotechnology white paper
NTP-CERHR expert panel report on hydroxyurea
EPA – special attention for risk assessment of metals
Pesticide tolerance petitions filed with the EPA
EPA pesticide tolerances for halosulfuron-methyl, orthosulfamuron and sethoxydim
REDs issued by EPA on pine oil, and propylene glycol and dipropylene glycol

OTHER AUTHORITATIVE BODIESMAK Value Documentations
DECOS occupational exposure limit for bitumen
NEG criteria document on microbial volatile organic compounds

PART II: SHORT CUTS

DEHP and male reproductive effects at low doses
Diethyl phthalate – liver effects across the generations
Triclopyr derivatives and developmental effects
Heptachlor linked with increased breast cancer risk
Prenatal exposure to hexachlorobenzene may affect early social skills
Genotoxicity of 4-monochlorobiphenyl
Manganese and human sperm
Inhalation of carbon nanotubes may adversely affect the cardiovascular system
Respiratory allergy to lasamide (2,4-dichloro-5-sulphamoylbenzoic acid)
PFOA impairs female mammary gland development in mice
Reproductive toxicity of dimethylsiloxanes
Oligonol is put through its paces
Developmental toxicity – testing time for D-ribose in rats
Mastic gum in 90-day rat feeding study
Vanadyl sulphate may affect reproductive function in male rats
Astaxanthin – accumulation is not just skin deep
Folic acid intake during pregnancy and facial clefts in babies
Vitamin A and stomach cancer
Antioxidant supplements – too much of a good thing?
Different flavonoids may protect against cancer of the oesophagus and kidney
Isoflavones – can they help prevent ovarian cancer?
Colon cancer and blueberry pterostilbene
Alcohol in pregnancy may adversely affect a child’s social development
Maternal diet and allergic diseases in children
Watercress, not just a garnish but a recipe for health?
Reduce cholesterol the chickpea way?
Modified 90-day feeding study may be needed for evaluating GM crops
Meat and kidney cancer
(Q)SAR models for mutagens and carcinogens

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