A newly updated (2009) bibra Toxicity Profile on methyl benzoate is now available, the summary of which is given below. Toxicity Profiles are comprehensive, yet concise, reviews on the hazard potential of individual chemicals. They are written by scientists specially trained in the evaluation of toxicity data and are prepared principally from primary information sources.

Methyl benzoate was not a skin sensitizer in humans tested with dilute solutions and failed to induce skin sensitization reactions in guinea pigs. It was irritant to the skin of rabbits and rats following repeated application, and caused mild eye effects in rabbits. Methyl benzoate was generally of low acute oral toxicity in laboratory animals, although oral or dermal exposures have induced effects on the central nervous system, blood and kidneys. In genotoxicity assays, methyl benzoate was not mutagenic in bacteria, and did not induce chromosome damage in a limited test using mammalian cells in culture. {26774}

The above item was taken from the October 2009 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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