A final EPA review considers the types, causes and underlying mechanisms of lymphohaematopoietic cancers. The report focuses in particular on leukaemia-inducing agents, and summarises the relevant data on several chemicals, including:
- ethylene oxide
- 1,3-butadiene
- formaldehyde (for which short overviews are presented)
- benzene
A discussion on the use of mechanistic information of leukaemia-inducing agents to inform the risk assessment process also features.
US Environmental Protection Agency (EPA). National Center for Environmental Assessment (NCEA).
Lymphohematopoietic cancers induced by chemicals and other agents: overview and implications for risk assessment (Final Report). EPA/600/R-10/095F, July 2012.
http://cfpub.epa.gov/ncea/cfm/recordisplay.cfm?deid=239589
The above item was taken from the August 2012 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).
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