In Silico Testing for Toxicology Assessment
Blog articles
Toxicity assessment is a key part of the drug discovery and development process. Many of the tests that use laboratory animals to investigate drug safety are time-consuming, expensive and complicated by ethical concerns. Investigative toxicology strategies have therefore adopted a tiered approach employing in silico and in vitro methods in order to ideally eliminate, or at least reduce, in vivo experimentation. Here, we attempt to give a simplified overview of the complex and multifaceted topic that is in silico toxicology assessment. Strap in and hold on tight…
Medical devices and CE certification
Blog articles
A medical device placed on the EU market must have a CE (“Conformité Européenne”) certification and comply with the EU Medical Devices Regulation (MDR; Regulation (EU) 2017/745) [1] or the EU In Vitro Diagnostic Medical Devices Regulation (IVDR; Regulation (EU) 2017/746) [2]. Read our overview on the process, plus find out how we can help.
Safe Cosmetic Testing Methods without Animals
Blog articles
Shampoo, perfume, lipstick, toothpaste – we all use at least some cosmetics in our everyday lives, and assume the manufacturers and regulatory agencies have our best health interests at heart. Here, we provide an overview on the use of laboratory animals in cosmetic safety testing, and discuss alternative non-animal-based test methods.
Aspartame: Hazard vs Risk (and why it’s got everyone in a tiff)
Blog articles
Earlier this month, The International Agency for Research on Cancer (IARC) classified the popular non-sugar sweetener aspartame as “possibly” carcinogenic to humans which has, understandably, raised concerns within industry and left a taste in consumers’ mouths that was far less sweet than they were used to.
The Expert Toxicologist has left the building. Or have they?
Blog articles
With generative Artificial Intelligence (AI) technology advancing rapidly, we look into AI generated toxicology content and decide whether or not we should “get our coats”.
The Importance of Safety Pharmacology Testing of Human Pharmaceuticals
Blog articles
Progression of a new pharmaceutical/drug from the laboratory to clinical trials requires it to have both a recognised health benefit and an acceptably-low risk of inducing adverse effects. By identifying undesirable effects and their underlying mechanisms, safety pharmacology studies are an essential component of the drug development process. Here, we’ll review the importance of safety pharmacology testing in human pharmaceuticals.
Biocompatibility Testing for Medical Devices: everything you need to know
Blog articles
Medical devices play a critical role in improving and maintaining human health. So why is biocompatibility important?
What is the role of Artificial Intelligence (AI) in toxicology?
Blog articles
The development of AI technologies promises to revolutionise every area of human endeavour – and toxicology is surely going to be no exception. Here we’ll examine how AI can be harnessed to improve efficiency and accuracy in toxicity assessment, risk evaluation and decision-making processes.