The summary and conclusions from JECFA’s 77th meeting (held in June 2013) are now available. The following developments are of particular interest:

  • An acceptable daily intake (ADI) of 5 mg/kg bw was assigned to advantame, based on maternal and developmental toxicity in rabbits.
  • Due to its low toxicity and low estimated dietary exposure, an ADI “not specified” was established for glucoamylase from, and expressed in, Trichoderma reesei.
  • The temporary group ADI of 12.5 mg/kg bw for glycerol ester of gum rosin (GEGR) and glycerol ester of wood rosin (GEWR) was withdrawn, and a new ADI of 25 mg/kg bw was established for GEWR.
  • For nisin, the previous ADI of 33,000 units/kg bw was withdrawn and an ADI of 0.7 mg/kg bw was established based on effects seen in rats.
  • The temporary ADI “not specified” was retained for octenyl succinic acid (OSA) modified gum arabic, pending submission of additional data on its stability in food (by the end of 2013).

Assessment of dietary exposure to cadmium from cocoa and cocoa products was also discussed.

Joint FAO/WHO Expert Committee on Food Additives. Seventy-seventh meeting, Rome, 4-13 June 2013. Summary and conclusions issued 19 June 2013. World Health Organization.



The above item was taken from the August 2013 issue of Toxicology and Regulatory News which is sent automatically to members of bibra (click here for more details).

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